Confirmatory Testing in Primary Aldosteronism

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Confirmatory testing in primary aldosteronism: extensive medication switching is not needed in all patients

OBJECTIVE Confirmatory testing of suspected primary aldosteronism (PA) requires an extensive medication switch that can be difficult for patients with severe complicated hypertension and/or refractory hypokalemia. For this reason, we investigated the effect of chronic antihypertensive medication on confirmatory testing results. To allow the results to be interpreted, the reproducibility of conf...

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Adrenal Venous Sampling in Patients With Positive Screening but Negative Confirmatory Testing for Primary Aldosteronism.

Adrenal venous sampling is considered to be the most reliable diagnostic procedure to lateralize aldosterone excess in primary aldosteronism (PA). However, normative criteria have not been established partially because of a lack of data in non-PA hypertensive patients. The aim of the study was to investigate aldosterone concentration and its gradient in the adrenal vein of non-PA hypertensive p...

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[Primary aldosteronism].

Franco Mantero, Gian Paolo Rossi, Enrico Agabiti Rosei Endocrine Unit, Department of Medical and Surgical Sciences, University of Padua, Italy Internal Medicine 4, Department of Clinical and Experimental Medicine, University of Padua, Italy Clinica Medica, Department of Medical and Surgical Sciences, University of Brescia, Italy European Society of Hypertension Scientific Newsletter: Update on ...

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Update in primary aldosteronism.

Primary aldosteronism (PA) is a condition well worth detecting because it is a common cause of hypertension and is associated with excessive morbidity for the degree of hypertension and reduced quality of life, all of which can be abrogated with specific surgical or medical treatment. Recent years have seen an explosion in knowledge concerning the genetic bases of this disorder, and particularl...

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ژورنال

عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism

سال: 2012

ISSN: 0021-972X,1945-7197

DOI: 10.1210/jc.2011-2504